microbial phytase

Increasing levels of phytase in corn-soybean meal diets increases the standardized total tract digestibility of Ca in soybean meal when fed to growing pigs

Calcium (Ca) is an essential macro mineral required for growth, bone development and remodeling, enzyme activity, cellular signaling, and metabolic regulation in swine (González-Vega and Stein, 2014). The concentration of Ca in diets and ingredients is a key feature because excess Ca decreases the digestibility of P and other nutrients and decreases feed intake and growth performance (Stein et al., 2011; Merriman et al., 2017; Lagos et al., 2019). Ideally, the requirement for Ca should be expressed as standardized total tract digestible (STTD) Ca instead of total Ca (NRC, 2012), which necessitates the generation of values for Ca digestibility in feed ingredients (Lautrou et al., 2020; Lee and Kong, 2022; Lee et al., 2023a). In plant feed ingredients, Ca concentration is low compared with inorganic sources; however, Ca in soybean meal (SBM) ranges from 0.25% to 0.75% (Sotak-Pepper et al., 2016; Lee et al., 2023a). Because SBM sometimes is included at high proportions in swine diets, Ca analysis of SBM is important to supplement diets with adequate quantities of additional Ca to meet requirements without including excess Ca in diets.

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Inclusion of microbial phytase in diets for growing pigs

Jaramillo, B. M., A. V. Hernandez, S. A Lee, M. Cristobal, and H. H. Stein. 2026. Inclusion of microbial phytase in diets for growing pigs. National Hog Farmer. On-line edition. April 30, 2026. Link to full text.

Effects of graded levels of phytase on apparent total tract digestibility of energy and concentrations of digestible and metabolizable energy in soybean meal

Soybean meal (SBM) is commonly used as a source of amino acids in swine diets because of its high protein content (Kudelka et al., 2021).  In addition, SBM contributes with energy and phosphorus (P). However, high portion of the P in SBM is bound to phytate, which is indigestible by pigs. Therefore, microbial phytase enzyme is supplemented in swine diets. The impact of phytase on the digestibility of P is well documented, however some experiments on digestibility in corn–SBM diets has been reported energy increase if microbial phytase was used (Liao et al., 2005; Arredondo et al., 2019; Lala et al., 2020; Espinosa et al., 2022), but, not in others (She et al., 2018; Mesina et al., 2019; Lamp and Moritz, 2022). There is, however, a lack of information about the impact of microbial phytase on the digestibility of energy in SBM. It is also not known if a possible effect of microbial phytase on energy digestibility in SBM is consistent among different sources of SBM.

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Effects of a novel microbial phytase on digestibility of P and Ca in diets fed to young growing pigs

Introduction

Pigs have a poor utilization of phytate-bound P derived from plant feed ingredients and supplemental phytase is, therefore, often used in pig diets (Selle and Ravindran, 2008), which is a very effective way to increase P digestibility. However, digestibility of Ca is also increased by phytase (Lee et al., 2023).

Bestzyme has recently been developed as a novel phytase, but there is limited information on how this phytase works on P and Ca digestibility. Therefore, the objective of this experiment was to test the hypothesis that a novel microbial phytase can replace some of the dietary P and Ca in diets for growing pigs without negatively impacting the standardized total tract digestibility (STTD) of P and Ca.

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Effects of novel microbial phytases on growth performance and bone ash of young growing pigs

Pigs have a poor utilization of phytate-bound P derived from plant feed ingredients and thus supplemental phytase is used in pig diets (Selle and Ravindran, 2008). Use of phytase in diets has been a very effective way to increase P digestibility, but the digestibility of amino acids, energy, and other minerals may also be increased by super dosing phytase (Kies et al., 2006; Arredondo et al., 2019), which ultimately increases growth performance and bone ash of pigs.

Bestzyme has recently been developed as a novel phytase, but there is limited information on how this phytase works on growth performance and bone ash of pigs. Therefore, the objective of this experiment was to test the hypothesis that dietary P and Ca in diets for growing pigs can be reduced without negatively impacting growth performance and bone ash of pigs if Bestzyme phytase is included in the diets.

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Effects of Reducing the Concentration of Ca and P and Increasing Microbial Phytase on Gastric Ph, Fecal Score, Growth Performance, and Bone Ash of Weanling Pigs

Lagos, L. V., M. R. Bedford, and H. H. Stein. 2021. Effects of Reducing the Concentration of Ca and P and Increasing Microbial Phytase on Gastric Ph, Fecal Score, Growth Performance, and Bone Ash of Weanling Pigs. J. Anim. Sci. 99(Suppl. 1): 44-45. doi.org/10.1093/jas/skab054.077 (Abstr.) Link to Abstract.

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Intrinsic phytase in hybrid rye increases the digestibility of phosphorus in corn and soybean meal in diets fed to growing pigs

Archs Toledo, Joan L., Su A Lee, Molly L. McGhee, Gonzalo G. Mateos, and Hans H. Stein. 2020. Intrinsic phytase in hybrid rye increases the digestibility of phosphorus in corn and soybean meal in diets fed to growing pigs. Journal of Animal Science, 2020, Vol. 98, No. 10, 1–6. doi:10.1093/jas/skaa295. Link to full text.